There are fundamental differences between the male and female brain which has been timelessly observed through all cultures. Science (neurology) has made breakthroughs in discovering exactly what those differences are.
The brain is divided into two halves, the left and right hemisphere. The left is the logic orientated side (generally), with very little emotional range or lateral creativity. The right side is the emotional and creative side (generally). The left can think with words, numbers, symbols. The right can think with feelings, visions, colours.
Men and woman have basic differences between the connections between those two sides of the brain. Most men and woman fit into the description, to varying degrees, but not always.
In the masculine brain there is very little connection (and therefore communication) between the two sides of the brain. They are either thinking rationally and logically with little emotion, or they are thinking emotionally with very little logic, with the left side of their brain. So if they are working on a problem solving exercise that they have very little emotion for (mathematics, engineering, finances, physics), they are completely rational with little emotion or creativity. However, if they are working on an emotive problem (eg. their loved dog is dying, they are in love, have a loved child who needs protection, just broke up with meaningful partner, like a song) that they feel strongly about, there is little logic and rationality, and they are using the right side of the brain. So if you are dealing with them when they are dealing with a logical problem, there is little point in trying to point out the emotive factors. Apply gain-orientated logic. If they are in an emotional state, there is little point in pointing out the rational factors (such as life will go on, or the logical processes involved). Apply feeling (sooth if upset, share the joy if happy). Ie. feel for them.
The feminine mind however, has a lot of connections (and therefore communication) between the two sides of the brain. The brain moves easily between emotional/creative thought and logical, rational thought. An example is "women's intuition". A female mind can feel something then apply logic. That's why they are capable of talking about emotions. If you are helping a female mind dealing with a problem, either logical or emotional, point out factors that make sense both logically and emotionally. Neither aspect can be ignored.
As stated before, your physical sex is an indication of your brain's sex, but different people show differing degrees of these connections. Occasionally people have brain's that are completely different from the norm.